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Article

Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator Dazl

25 May 2007

Abstract excerpt

DAZ-related genes are essential for gametogenesis in diverse metazoa: in human males, a loss of DAZ genes is associated with infertility. These genes, expressed only in germ cells, regulate the translation of a yet undefined set of specific transcripts, and loss of function results in numerous defects throughout the mitotic and meiotic process of germ cell development. In a mouse model, absence of the autosomal...

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Share to Chromosomal and Genetic Variations
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PMID: 17526644
DOI: 10.1261/rna.465507

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Translation of the synaptonemal complex component Sycp3 is enhanced in vivo by the germ cell specific regulator DazlPMID 17526644Read ↗

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DAZ Family Proteins, Key Players for Germ Cell DevelopmentSemantic proximity Read ↗

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