In vitro and in vivo characterization of herpes simplex virus clinical isolates recovered from patients infected with human immunodeficiency virus.

doi:10.1128/AAC.35.11.2322

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Article

In vitro and in vivo characterization of herpes simplex virus clinical isolates recovered from patients infected with human immunodeficiency virus.

Antimicrobial agents and chemotherapy - 1 Nov 1991

Hill E L, Hunter G A, Ellis M N

Abstract excerpt

A total of 100 herpes simplex viruses isolated from lesions not responding to acyclovir (ACV) therapy were recovered from 51 patients infected with human immunodeficiency virus. In vitro analysis of these isolates included testing their susceptibility to ACV and determining their thymidine kinase...

Topics

Animals
Autoradiography
Ganglia
HIV Infections
Herpes Simplex
Mice
Mice, Hairless
Mice, Inbred BALB C
Phenotype
Simplexvirus
Thymidine Kinase
Viral Plaque Assay

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