Article
Extraordinary variation in a diversified family of immune-type receptor genes.
Proceedings of the National Academy of Sciences of the United States of America - 20 Nov 2001
Hawke N A, Yoder J A, Haire R N, Mueller M G, Litman R T, Miracle A L, Stuge T, Shen L, Miller N, Litman G W
Abstract excerpt
Immune inhibitory receptor genes that encode a variable (V) region, a unique V-like C2 (V/C2) domain, a transmembrane region, and a cytoplasmic tail containing immunoreceptor tyrosine-based inhibition motifs (ITIMs) have been described previously in two lineages of bony fish. In the present study, eleven related genes encoding distinct structural forms have been identified in Ictalurus punctatus (channel...
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