Article
Identification and characterisation of a novel immune-type receptor (NITR) gene cluster in the European sea bass, Dicentrarchus labrax, reveals recurrent gene expansion and diversification by positive selection.
Immunogenetics - 1 Dec 2009
Ferraresso Serena, Kuhl Heiner, Milan Massimo, Ritchie David W, Secombes Christopher J, Reinhardt Richard, Bargelloni Luca
Abstract excerpt
In the last decade, a new gene family encoding non-rearranging receptors, called novel immune-type receptors (NITRs), has been discovered in teleost fish. NITRs belong to the immunoglobulin superfamily and represent an extraordinarily divergent and rapidly evolving gene complex. Genomic analysis of a region spanning 270 kb led to the discovery of a NITR gene cluster in the European sea bass (Dicentrarchus...
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