Article
Genomic and functional characterization of the diverse immunoglobulin domain-containing protein (DICP) family.
Genomics - 1 May 2012
Haire Robert N, Cannon John P, O'Driscoll Marci L, Ostrov David A, Mueller M Gail, Turner Poem M, Litman Ronda T, Litman Gary W, Yoder Jeffrey A
Abstract excerpt
A heretofore-unrecognized multigene family encoding diverse immunoglobulin (Ig) domain-containing proteins (DICPs) was identified in the zebrafish genome. Twenty-nine distinct loci mapping to three chromosomal regions encode receptor-type structures possessing two classes of Ig ectodomains (D1 and D2). The sequence and number of Ig domains, transmembrane regions and signaling motifs vary between DICPs....
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