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Article

Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein.

The Journal of biological chemistry - 25 Jan 2002

Saville Bradley, Poukka Hetti, Wormke Mark, Janne Olli A, Palvimo Jorma J, Stoner Matthew, Samudio Ismael, Safe Stephen

Abstract excerpt

SNURF is a small RING finger protein that binds the zinc finger region of steroid hormone receptors and enhances Sp1- and androgen receptor-mediated transcription in COS and CV-1 cells. In this study, we show that SNURF coactivates both wild-type estrogen receptor alpha (ERalpha) (4-fold)- and HE19 (ERalpha deletion of activation function 1 (AF1)) (210-fold)-mediated activation of an estrogen-responsive element...

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Source

Identifiers

PMID: 11696545
DOI: 10.1074/jbc.M109021200

Genes

TBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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