Article
Small nuclear RING finger protein stimulates the rat luteinizing hormone-beta promoter by interacting with Sp1 and steroidogenic factor-1 and protects from androgen suppression.
Molecular endocrinology (Baltimore, Md.) - 1 May 2004
Curtin Denis, Ferris Heather A, Häkli Marika, Gibson Matthew, Jänne Olli A, Palvimo Jorma J, Shupnik Margaret A
Abstract excerpt
GnRH controls expression of the LH subunit genes, alpha and LHbeta, with the LHbeta subunit regulated most dramatically. Two enhancer regions, distal and proximal, on the rat LHbeta gene promoter cooperate for full basal expression and GnRH stimulation. It has been hypothesized that the transcrip...
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