Article
Diversity of MICA (PERB11.1) and HLA haplotypes in Northeastern Thais.
Tissue antigens - 1 Aug 2001
Romphruk A V, Naruse T K, Romphruk A, Kawata H, Puapairoj C, Kulski J K, Leelayuwat C, Inoko H
Abstract excerpt
MICA or PERB11.1 is a polymorphic major histocompatibility complex (MHC) class I-related gene located 46 kb centromeric of the HLA-B gene in the HLA class I region. It is expressed mainly in gut epithelial cells, keratinocytes, endothelial cells, fibroblasts and monocytes, and is upregulated by heat stress. MICA has been found to interact with gamma delta T cells, alpha beta CD8(+) and natural killer (NK) cells...
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