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Article

Long-term administration of amlodipine prevents decompensation to diastolic heart failure in hypertensive rats.

Journal of the American College of Cardiology - 1 Nov 2001

Nishikawa N, Masuyama T, Yamamoto K, Sakata Y, Mano T, Miwa T, Sugawara M, Hori M

Abstract excerpt

UNLABELLED: OBJECTIVES; We assessed the effects of long-term amlodipine administration in a diastolic heart failure (DHF) rat model with preserved systolic function as well as the relationship between changes in left ventricular (LV) myocardial stiffening and alterations in extracellular matrix. BACKGROUND: Although the effect of long-term administration of amlodipine has been shown to be disappointing in...

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Source

Identifiers

PMID: 11691537
DOI: 10.1016/s0735-1097(01)01548-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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