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Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes

10 Oct 2009

Abstract excerpt

The aim of this paper is to study the myocardial damage secondary to long-term streptozotocin-induced type 1 diabetes mellitus (DM1). Normotensive and spontaneously hypertensive rats (SHR) received either streptozotocin injections or vehicle. After 22 or 6 wk, DM1, SHR, DM1/SHR, and control rats were killed, and the left ventricles studied by histology, quantitative PCR, Western blot, ELISA, and electromobility...

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Identifiers

PMID: 19820199
DOI: 10.1152/ajpheart.00157.2009

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