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Article

Selection analyses of insertional mutants using subgenic-resolution arrays.

Nature biotechnology - 1 Nov 2001

Badarinarayana V, Estep P W, Shendure J, Edwards J, Tavazoie S, Lam F, Church G M

Abstract excerpt

We describe a method of genome-wide analysis of quantitative growth phenotypes using insertional mutagenesis and DNA microarrays. We applied the method to assess the fitness contributions of Escherichia coli gene domains under specific growth conditions. A transposon library was subjected to competitive growth selection in Luria-Bertani (LB) and in glucose minimal media. Transposon-containing genomic DNA...

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PMID: 11689852
DOI: 10.1038/nbt1101-1060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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