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Article

Critical Roles of Nuclear Receptor Response Elements in Replication of Hepatitis B Virus

1 Dec 2001

Abstract excerpt

Functional analysis of the roles of the nuclear receptor response elements (NRREs) in the transcription and replication of hepatitis B virus (HBV) in the context of its whole genome has been hampered by the extensive overlapping of the NRREs with the regions encoding viral proteins. We introduced point mutations that inactivate the NRREs individually without altering the open reading frames of viral proteins....

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PMID: 11689616
DOI: 10.1128/jvi.75.23.11354-11364.2001

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