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Article

Regulation of extravascular coagulation and fibrinolysis by heparin-dependent mast cell chymase.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Dec 2001

Tchougounova E, Pejler G

Abstract excerpt

We recently characterized a heparin-deficient mouse strain generated by targeting the gene for N-deacetylase/N-sulfotransferase-2 (NDST-2). The NDST-2-/- mice show severe defects in their organization of mast cell (MC) secretory granules, with an almost total absence of the various heparin-binding MC proteases. In the present report we have studied the consequences of heparin/MC protease deficiency for...

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Identifiers

PMID: 11687508
DOI: 10.1096/fj.01-0486fje

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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