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Article

Mast Cells Granular Contents Are Crucial for Deep Vein Thrombosis in Mice.

Circulation research - 29 Sept 2017

Ponomaryov Tatyana, Payne Holly, Fabritz Larissa, Wagner Denisa D, Brill Alexander

Abstract excerpt

RATIONALE: Deep vein thrombosis (DVT) and its complication pulmonary embolism have high morbidity reducing quality of life and leading to death. Cellular mechanisms of DVT initiation remain poorly understood. OBJECTIVE: We sought to determine the role of mast cells (MCs) in DVT initiation and validate MCs as a potential target for DVT prevention. METHODS AND RESULTS: In a mouse model, DVT was induced by partial...

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Identifiers

PMID: 28739590
DOI: 10.1161/CIRCRESAHA.117.311185
PMCID: PMC5623089

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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