Article
Regulation of human lung fibroblast phenotype and function by vitronectin and vitronectin integrins.
Journal of cell science - 1 Oct 2001
Scaffidi A K, Moodley Y P, Weichselbaum M, Thompson P J, Knight D A
Abstract excerpt
Myofibroblasts, characterised by high expression of alpha-smooth muscle actin (alpha-SMA), are important and transient cells in normal wound healing but are found in increased number in various pathological conditions of the lung including asthma and pulmonary fibrosis. The mechanisms that regulate the myofibroblast phenotype are unknown but are likely to involve signals from the extracellular matrix transmitted...
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