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Article

Epistasis between new mutations and genetic background and a test of genetic canalization.

Evolution; international journal of organic evolution - 1 Sept 2001

Elena S F, Lenski R E

Abstract excerpt

The importance for fitness of epistatic interactions among mutations is poorly known, yet epistasis can exert important effects on the dynamics of evolving populations. We showed previously that epistatic interactions are common between pairs of random insertion mutations in the bacterium Escherichia coli. In this paper, we examine interactions between these mutations and other mutations by transducing each of...

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PMID: 11681730
DOI: 10.1111/j.0014-3820.2001.tb00824.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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