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Article

Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis.

The Journal of biological chemistry - 14 Dec 2001

Ye K, Zhou J, Landen J W, Bradbury E M, Joshi H C

Abstract excerpt

Mitotic arrest and subsequent apoptosis has been observed in many types of cells treated with anti-microtubule agents. However, the molecular mechanisms underlying the two events as well as their relationship are not well understood; on the contrary, there has been increasing evidence indicating that anti-microtubule agents might induce apoptosis via signaling pathways independent of mitosis. In this study, we...

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PMID: 11679575
DOI: 10.1074/jbc.C100550200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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