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Article

EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells

30 Oct 2009

Abstract excerpt

BACKGROUND: Lung cancer remains a leading cause of cancer death among both men and women in the United States. Treatment modalities available for this malignancy are inadequate and thus new drugs with improved pharmacological profiles and superior therapeutic indices are being continually explored. Noscapinoids constitute an emerging class of anticancer agents that bind tubulin but do not significantly alter the...

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PMID: 19878573
DOI: 10.1186/1476-4598-8-93

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