Article
A simple correction for multiple comparisons in interval mapping genome scans.
Heredity - 1 Jul 2001
Cheverud J M
Abstract excerpt
Several approaches have been proposed to correct point-wise significance thresholds used in interval-mapping genome scans. A method for significance threshold correction based on the Bonferroni test is presented. This test involves calculating the effective number of independent comparisons performed in a genome scan from the variance of the eigenvalues of the observed marker correlation matrix. The more highly...
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