Article
Association between endometriosis and N-acetyl transferase 2 polymorphisms in a UK population.
Molecular human reproduction - 1 Nov 2001
Nakago S, Hadfield R M, Zondervan K T, Mardon H, Manek S, Weeks D E, Barlow D, Kennedy S
Abstract excerpt
The relationship between endometriosis and polymorphisms in the N-acetyl transferase 2 (NAT 2) gene was investigated in a UK population, as this gene has been previously implicated in the aetiology of the disease. Point mutations in the gene result in the variant alleles NAT 2 *5, *6 and *7 from the wild-type NAT 2 *4 allele. Homozygotes for the NAT 2 *4 wild type allele are fast NAT acetylators, while...
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