Article
N-acetyltransferase 2 genotype in colorectal cancer and selective gene retention in cancers with chromosome 8p deletions.
Gut - 1 Aug 1997
Hubbard A L, Harrison D J, Moyes C, Wyllie A H, Cunningham C, Mannion E, Smith C A
Abstract excerpt
BACKGROUND: Genetic polymorphisms in N-acetyltransferase (NAT2) can change the normally fast acetylation of substrates to slow acetylation, and have been associated with the development of some cancers. The NAT2 locus may also suffer dysregulation during cancer progression, as the gene resides on...
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