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Article

Spontaneous and radiation-induced leukemogenesis of the mouse small eye mutant, Pax6(Sey3H).

Journal of radiation research - 1 Jun 2004

Nitta Yumiko, Yoshida Kazuko, Satoh Kenichi, Senba Kei, Nakagata Naomi, Peters Jo, Cattanach Bruce M

Abstract excerpt

Allelic loss on the chromosome 2 is associated with radiation-induced murine acute myeloid leukemia. However, the gene, which contributes mainly to the leukemogenesis has not yet been identified. Expecting any predisposition to acute myeloid leukemia, we performed a radiation leukemogenensis experiment with Pax6(Sey3H), one of the small eye mutants carrying a congenital hemizygosity of the chromosome 2 middle...

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PMID: 15304967
DOI: 10.1269/jrr.45.245

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