Article
In vivo andin vitro studies of adaptor-clathrin interaction.
Journal of visualized experiments : JoVE - 26 Jan 2011
Feliciano Daniel, Bultema Jarred J, Ambrosio Andrea L, Di Pietro Santiago M
Abstract excerpt
A major endocytic pathway initiates with the formation of clathrin-coated vesicles (CCVs) that transport cargo from the cell surface to endosomes. CCVs are distinguished by a polyhedral lattice of clathrin that coats the vesicle membrane and serves as a mechanical scaffold. Clathrin coats are assembled during vesicle formation from individual clathrin triskelia , the soluble form of clathrin composed of three...
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