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Article

Key interactions for clathrin coat stability.

Structure (London, England : 1993) - 10 Jun 2014

Böcking Till, Aguet François, Rapoport Iris, Banzhaf Manuel, Yu Anan, Zeeh Jean Christophe, Kirchhausen Tom

Abstract excerpt

Clathrin-coated vesicles are major carriers of vesicular traffic in eukaryotic cells. This endocytic pathway relies on cycles of clathrin coat assembly and Hsc70-mediated disassembly. Here we identify histidine residues as major determinants of lattice assembly and stability. They are located at the invariant interface between the proximal and distal segments of clathrin heavy chains, in triskelions centered on...

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Identifiers

PMID: 24815030
DOI: 10.1016/j.str.2014.04.002
PMCID: PMC4067485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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