The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat.

Article

The role of the neuroendocrine system in determining genetic susceptibility to experimental allergic encephalomyelitis in the rat.

Immunology - 1 May 1990

Mason D, MacPhee I, Antoni F

Abstract excerpt

Experimental allergic encephalomyelitis (EAE) can be induced in some strains of rat but not others, by the injection of guinea-pig myelin basic protein in Freund's complete adjuvant. In the susceptible Lewis strain, spontaneous recovery from paralysis occurs and previous studies have shown that t...

Topics

Adrenalectomy
Animals
Corticosterone
Encephalomyelitis, Autoimmune, Experimental
Genetic Predisposition to Disease
Major Histocompatibility Complex
Rats
Rats, Inbred Strains

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