Article
Rifampin resistance in Mycobacterium kansasii is associated with rpoB mutations.
Antimicrobial agents and chemotherapy - 1 Nov 2001
Klein J L, Brown T J, French G L
Abstract excerpt
Rifampin is the most potent drug used in the treatment of disease due to Mycobacterium kansasii. A 69-bp fragment of rpoB, the gene that encodes the beta subunit of the bacterial RNA polymerase, was sequenced and found to be identical in five rifampin-susceptible clinical isolates of M. kansasii....
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