Article
Biological characterization of three novel variants of IFN-alpha 13 produced by human placental trophoblast.
Placenta - 1 Jan 2000
Fink T, Zachar V, Ebbesen P
Abstract excerpt
Interferon (IFN)-alpha from the human placenta was cloned and expressed with the aim to study the antiviral, antiproliferative, and immunostimulatory activities. In the present study, we describe three previously unknown sequence variants of IFN-alpha 13 originating from the villous trophoblast. The first variant differed from IFN-alpha 13 by a Cys99Arg substitution and a 10-amino acid C-terminal deletion, which...
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