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Article

Interferon Gamma in Successful Pregnancies1

22 Jan 2009

Abstract excerpt

Interferon gamma (IFNG) is a proinflammatory cytokine secreted in the uterus during early pregnancy. It is abundantly produced by uterine natural killer cells in maternal endometrium but also by trophoblasts in some species. In normal pregnancies of mice, IFNG plays critical roles that include initiation of endometrial vasculature remodeling, angiogenesis at implantation sites, and maintenance of the decidual...

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PMID: 19164174
DOI: 10.1095/biolreprod.108.073353

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