Article
Assessing linkage disequilibrium in a complex genetic system. I. Overall deviation from random association.
Annals of human genetics - 1 Mar 1999
Zhao H, Pakstis A J, Kidd J R, Kidd K K
Abstract excerpt
Linkage disequilibrium is an important tool both at the end stages of positional cloning studies to map genes of particular interest and in reconstruction of population histories. With advances in molecular biology, complex genetic systems involving multiple highly polymorphic markers are becoming more commonly used to study linkage disequilibrium. These systems contain much more genetic information than simple...
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