Article
The role of constitutive NF-kappaB activity in PC-3 human prostate cancer cell invasive behavior.
Clinical & experimental metastasis - 1 Jan 2000
Lindholm P F, Bub J, Kaul S, Shidham V B, Kajdacsy-Balla A
Abstract excerpt
The purpose of this study was to determine if increased NF-kappaB activity of highly invasive PC-3 cells contributed to their invasive behavior. Increased NF-kappaB activity has been observed in several malignant tumors and it may have an important role in tumorigenesis, progression and chemotherapy resistance. By serial selection, we obtained invasion variant PC-3 cell sublines. The PC-3 High Invasive cells...
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