[Mutations in the mitochondrial gene in patients with NIDDM].

Abstract excerpt

Since the identification of an A to G mutation at position 3243 of mitochondrial leucine tRNA (3243 bp mutation) in families with diabetes and deafness, the prevalence, clinical characteristics, pathophysiology of diabetes associated with 3243 bp mutation have been studied in Japan. Our study has shown that diabetes cosegregates with 3243 bp mutation in more than 30 Japanese families and that the prevalence of...

Topics

• Asian People
• Diabetes Mellitus, Type 2
• Humans
• Japan
• Mitochondria
• Mutation