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Article

Role of the kinetochore protein Ndc10 in mitotic checkpoint activation in Saccharomyces cerevisiae.

Molecular genetics and genomics : MGG - 1 Sept 2001

Fraschini R, Beretta A, Lucchini G, Piatti S

Abstract excerpt

Mitotic checkpoints delay cell cycle progression in response to alterations in the mitotic apparatus, thus ensuring correct chromosome segregation. While improper spindle orientation activates the Bub2/Bfa1-dependent checkpoint in budding yeast, delaying exit from mitosis, lack of bipolar kinetochore-microtubule attachment activates a signal transduction cascade that prevents both anaphase onset and exit from...

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PMID: 11589568
DOI: 10.1007/s004380100533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of the kinetochore protein Ndc10 in mitotic checkpoint activation in Saccharomyces cerevisiae.PMID 11589568Read ↗

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