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Article

Common regulation of growth arrest and differentiation of osteoblasts by helix-loop-helix factors.

Molecular and cellular biology - 1 Nov 2001

Funato N, Ohtani K, Ohyama K, Kuroda T, Nakamura M

Abstract excerpt

Cellular differentiation entails the coordination of cell cycle arrest and tissue-specific gene expression. We investigated the involvement of basic helix-loop-helix (bHLH) factors in differentiation of osteoblasts using the human osteoblastic cell line MG63. Serum starvation induced growth arrest at G1 phase, accompanied by expression of cyclin-dependent kinase inhibitor p21(WAF1/Cip1). Reporter assays with the...

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Identifiers

PMID: 11585922
DOI: 10.1128/MCB.21.21.7416-7428.2001
PMCID: PMC99914

Genes

FGFR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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