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Article

AIF-1 expression defines a proliferating and alert microglial/macrophage phenotype following spinal cord injury in rats.

Journal of neuroimmunology - 1 Oct 2001

Schwab J M, Frei E, Klusman I, Schnell L, Schwab M E, Schluesener H J

Abstract excerpt

Microglial cells are among the first and dominant cell types to respond to CNS injury. Following calcium influx, microglial activation leads to a variety of cellular responses, such as proliferation and release of cytotoxic and neurotrophic mediators. Allograft inflammatory factor-1, AIF-1 is a highly conserved EF-handed, putative calcium binding peptide, associated with microglia activation in the brain. Here,...

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PMID: 11585624
DOI: 10.1016/s0165-5728(01)00375-7

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PCNA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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