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Expression of two temporally distinct microglia‐related gene clusters after spinal cord injury

12 Dec 2005

Abstract excerpt

The dual role of microglia in cytotoxicity and neuroprotection is believed to depend on the specific, temporal expression of microglial-related genes. To better clarify this issue, we used high-density oligonucleotide microarrays to examine microglial gene expression after spinal cord injury (SCI) in rats. We compared expression changes at the lesion site, as well as in rostral and caudal regions after mild,...

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PMID: 16345062
DOI: 10.1002/glia.20295

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