Article
Stem cell properties and repopulation of the rat liver by fetal liver epithelial progenitor cells.
The American journal of pathology - 1 Oct 2001
Sandhu J S, Petkov P M, Dabeva M D, Shafritz D A
Abstract excerpt
The potential of embryonal day (ED) 14 fetal liver epithelial progenitor (FLEP) cells from Fischer (F)344 rats to repopulate the normal and retrorsine-treated liver was studied throughout a 6-month period in syngeneic dipeptidyl peptidase IV (DPPIV-) mutant F344 rats. In normal liver, FLEP cells formed: 1) hepatocytic clusters ranging in size up to approximately 800 to 1000 cells; 2) bile duct structures...
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