Isolation of human progenitor liver epithelial cells with extensive replication capacity and differentiation into mature hepatocytes

Abstract excerpt

The liver can regenerate itself through the progenitor cells it harbors. Here we demonstrate isolation of epithelial progenitor/stem cells from the fetal human liver, which contains a large number of hepatoblasts. Progenitor liver cells displayed clonogenic capacity, expressed genes observed in hepatocytes, bile duct cells and oval cells, and incorporated genes transferred by adenoviral or lentiviral vectors....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Liver physiology and pathology
• Share to Organ Transplantation Techniques and Outcomes
• Share to Pediatric Hepatobiliary Diseases and Treatments