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Article

Timing and sequence of differentiation of embryonic rat hepatocytes along the biliary epithelial lineage.

Hepatology (Baltimore, Md.) - 1 Sept 2003

Notenboom Robbert G E, van den Bergh Weerman Marius A, Dingemans Koert P, Vermeulen Jacqueline L M, van den Eijnde Stefan, Reutelingsperger Chris P, Hut Hans, Willemsen Rob, Offerhaus G Johan A, Lamers Wouter H

Abstract excerpt

To study the differentiation of hepatocytes along the biliary epithelial lineage in vivo, embryonic day 14 (E14) rat hepatocytes were isolated by differential centrifugation and transplanted as single-cell suspensions into the spleen of adult syngeneic rats. Hepatocytes and cholangiocytes were identified and their maturation characterized by the level of expression of alpha-fetoprotein (AFP), glutamate...

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PMID: 12939595
DOI: 10.1053/jhep.2003.50365

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AFP
CFTR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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