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Article

Signal transduction by VEGF receptor-1 wild type and mutant proteins.

Cellular signalling - 1 Nov 2001

Ito N, Huang K, Claesson-Welsh L

Abstract excerpt

The role of the vascular endothelial growth factor receptor-1 (VEGFR-1) in endothelial cell function is unclear. We have previously identified four tyrosine phosphorylation sites in the C-terminal tail of this receptor. We now show that the wild type VEGFR-1 expressed in porcine aortic endothelial (PAE/VEGFR-1) cells was able to transduce signals for increased DNA synthesis and proliferation. Tyrosine...

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Source

Identifiers

PMID: 11583921
DOI: 10.1016/s0898-6568(01)00209-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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