Article

Differences in Activation of Intracellular Signalling in Primary Human Retinal Endothelial Cells Between Isoforms of VEGFA-165

2019-12-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> There are reports that a b-isoform of Vascular Endothelial Growth Factor-A-165 (VEGFA 165 b) is predominant in normal human vitreous, switching to the a-isoform (VEGFA 165 a) in the vitreous of some diseased eyes. While these isoforms appear to have a different ability to activate the VEGF-Receptor-2 (VEGFR2) in various endothelial cells, the nature of their ability to activa...

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Literature Corpus work: e3a53336-5297-590c-b0fb-b766d70b7768
DOI: 10.1101/2019.12.12.871947

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