Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Multiple Immune-Evasion Genes of Murine Cytomegalovirus Are Not Redundant

1 Oct 2001

Abstract excerpt

Both human cytomegaloviruses (HCMVs) and murine cytomegaloviruses (MCMVs) encode multiple genes that interfere with antigen presentation by major histocompatibility complex (MHC) class I, and thus protect infected targets from lysis by virus-specific cytotoxic T lymphocytes (CTLs). HCMV has been shown to encode four such genes and MCMV to encode two. MCMV m152 blocks the export of class I from a pre-Golgi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Immune Cell Function and Interaction
Share to Toxoplasma gondii Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11581318
DOI: 10.1084/jem.194.7.967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Multiple Immune-Evasion Genes of Murine Cytomegalovirus Are Not RedundantPMID 11581318Read ↗

Cytomegaloviral control of MHC class I function in the mouse.Semantic proximity Read ↗

The immunoevasive function encoded by the mouse cytomegalovirus gene m152 protects the virus against T cell control in vivo.Semantic proximity Read ↗

Major histocompatibility complex class I allele-specific cooperative and competitive interactions between immune evasion proteins of cytomegalovirus.Semantic proximity Read ↗

Cytomegalovirus Misleads Its Host by Priming of CD8 T Cells Specific for an Epitope Not Presented in Infected TissuesSemantic proximity Read ↗

Coordinated function of murine cytomegalovirus genes completely inhibits CTL lysis.Semantic proximity Read ↗

How the Virus Outsmarts the Host: Function and Structure of Cytomegalovirus MHC‐I‐Like Molecules in the Evasion of Natural Killer Cell SurveillanceSemantic proximity Read ↗

Viral interference with antigen presentation to CD8+ T cells: lessons from cytomegalovirus.Semantic proximity Read ↗

Viral Interference with Antigen Presentation Does Not Alter Acute or Chronic CD8 T Cell Immunodominance in Murine Cytomegalovirus InfectionSemantic proximity Read ↗

Cytomegalovirus immune evasion sets the functional avidity threshold for protection by CD8 T cellsSemantic proximity Read ↗

Cutting Edge: Murine Cytomegalovirus Induces a Polyfunctional CD4 T Cell ResponseSemantic proximity Read ↗

Subversion of Immune Response by Human CytomegalovirusSemantic proximity Read ↗

Murine cytomegalovirus degrades MHC class II to colonize the salivary glandsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.