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Article

Cytomegaloviral control of MHC class I function in the mouse.

Immunological reviews - 1 Apr 1999

Hengel H, Reusch U, Gutermann A, Ziegler H, Jonjic S, Lucin P, Koszinowski U H

Abstract excerpt

Cytomegaloviruses (CMVs) represent prototypic viruses of the beta-subgroup of herpesviruses. Murine cytomegalovirus (MCMV) infects mice as its natural host. Among viruses, CMVs have evolved the most extensive genetic repertoire to subvert MHC class I functions. To date three MCMV proteins have been identified which affect MHC I complexes. They are encoded by members of large virus-specific gene families located...

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PMID: 10399073
DOI: 10.1111/j.1600-065x.1999.tb01291.x

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