Article
Major histocompatibility complex class I allele-specific cooperative and competitive interactions between immune evasion proteins of cytomegalovirus.
The Journal of experimental medicine - 16 Sept 2002
Wagner Markus, Gutermann Anja, Podlech Jürgen, Reddehase Matthias J, Koszinowski Ulrich H
Abstract excerpt
Cytomegaloviruses (CMVs) deploy a set of genes for interference with antigen presentation in the major histocompatibility complex (MHC) class I pathway. In murine CMV (MCMV), three genes were identified so far: m04/gp34, m06/gp48, and m152/gp40. While their function as immunoevasins was originally defined after their selective expression, this may not necessarily reflect their biological role during infection....
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