Article
A novel C-terminal kinesin is essential for maintaining functional acidocalcisomes in Trypanosoma brucei.
The Journal of biological chemistry - 28 Dec 2001
Dutoya S, Gibert S, Lemercier G, Santarelli X, Baltz D, Baltz T, Bakalara N
Abstract excerpt
Kinesins are cytoskeletal motor proteins that play roles in a variety of fundamental cellular processes including cell division and the anterograde transport of vesicles and organelles. We purified, cloned, and functionally characterized in Trypanosoma brucei a new member of the C-terminal kinesin family, TbKIFC1. Kinetic constants of the recombinant motor domain of TbKIFC1 were estimated at 0.56 microm for the...
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