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A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei

15 Jun 2021

Abstract excerpt

In eukaryotic cells, kinetochores are large protein complexes that link chromosomes to dynamic microtubule tips, ensuring proper segregation and genomic stability during cell division. Several proteins tightly coordinate kinetochore functions, including the protein kinase aurora kinase B. The kinetochore has diverse evolutionary roots. For example, trypanosomatids, single-cell parasitic protozoa that cause...

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PMID: 34128702
DOI: 10.1128/mbio.00687-21

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A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma bruceiPMID 34128702Read ↗

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