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Article

EmtA, a rRNA methyltransferase conferring high‐level evernimicin resistance

1 Sept 2001

Abstract excerpt

Enterococcus faecium strain 9631355 was isolated from animal sources on the basis of its resistance to the growth promotant avilamycin. The strain also exhibited high-level resistance to evernimicin, a drug undergoing evaluation as a therapeutic agent in humans. Ribosomes from strain 9631355 exhibited a dramatic reduction in evernimicin binding, shown by both cell-free translation assays and direct-binding...

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PMID: 11580839
DOI: 10.1046/j.1365-2958.2001.02602.x

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EmtA, a rRNA methyltransferase conferring high‐level evernimicin resistancePMID 11580839Read ↗

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