Article
Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia
25 Sept 2001
Abstract excerpt
Fluorescence in situ hybridization (FISH) studies were performed in three cases of acute lymphoblastic leukemia (ALL) with marker chromosomes to analyze the contribution of chromosome 21 in these markers. FISH with a chromosome 21 painting probe confirmed that chromosome 21 was involved in all three cases. FISH with YAC probes showed that the number of extra copies varied according to their location on chromosome...
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