Article
Complex variant t(4;11) characterized by fluorescence in situ hybridization in infant acute lymphoblastic leukemia.
Cancer genetics and cytogenetics - 1 Jun 2001
Sharma P, Jarvis A, Jauch A, St Heaps L, Shaw P, Smith A
Abstract excerpt
A 6-month-old girl was diagnosed with acute lymphoblastic leukemia (ALL). Chromosome analysis of bone marrow aspirate showed 46,XX,t(4;11)(q21;q23) with an atypical appearance of the 11p on the der(11) chromosome. FISH studies to fully characterize the translocation utilised 8 probes: whole chromosome painting probes for chromosome 11 and chromosome 4; separate chromosome 11 short arm and long arm paints;...
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