Article
Interferon-Induced Rat Mx Proteins Confer Resistance to Rift Valley Fever Virus and Other Arthropod-Borne Viruses
1 Sept 2001
Abstract excerpt
Mx proteins belong to the interferon (IFN)-induced antiviral defense. The rat genome contains three Mx genes, ratMx1, ratMx2, and ratMx3. The Mx gene products differ in their subcellular localization and antiviral specificity. The nuclear ratMx1 protein confers resistance to influenza A virus, and the cytoplasmic ratMx2 is active against vesicular stomatitis virus (VSV), whereas the cytoplasmic ratMx3 protein is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
