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Interferon-Inducible Mx Gene Expression in Cotton Rats: Cloning, Characterization, and Expression During Influenza Viral Infection

1 Dec 2006

Abstract excerpt

Mx proteins belong to the superfamily of large GTPases with antiviral activity against a wide range of RNA viruses. In vivo, the expression of Mx genes is tightly regulated by the presence of type I interferons (IFNs), and their induction has been described during several viral infections. However, because of the absence of functional Mx genes in most common laboratory strains of mice, in vivo studies of the...

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PMID: 17238834
DOI: 10.1089/jir.2006.26.914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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